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primary human kupffer cells npc-ad-kc  (LifeNet Health Inc)

 
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    LifeNet Health Inc primary human kupffer cells npc-ad-kc
    Immune-mediated toxicity in the PhysioMimix LC12. Changes in LDH, CYP3A4, and IL-6 after 48 h trovafloxacin exposure with and without LPS in the PhysioMimix LC12 seeded with PHHs (donor HU8373) and non-parenchymal cells (THP-1 cells or <t>Kupffer</t> <t>cells).</t> ( A ) LDH leakage, ( B ) CYP3A4 activity, and ( C ) IL-6 release. Endpoints were normalized to the mean of the pretreatment samples (day 6 of the experiment). Data are plotted as box (interquartile range) and whiskers (min-max) with all individual values shown (n = 2–12). The red dotted line shows 100% (mean of the pretreatment samples). Brackets indicate statistical significance between groups at p < 0.05 by two-way ANOVA with Tukey’s multiple comparisons test.
    Primary Human Kupffer Cells Npc Ad Kc, supplied by LifeNet Health Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/primary+human+kupffer+cells+npc-ad-kc/primary+human+kupffer+cells+npc+ad+kc/pmc10603899-104-0-19
    Average 90 stars, based on 1 article reviews
    primary human kupffer cells npc-ad-kc - by Bioz Stars, 2026-09
    90/100 stars

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    1) Product Images from "Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations"

    Article Title: Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations

    Journal: Bioengineering

    doi: 10.3390/bioengineering10101195

    Immune-mediated toxicity in the PhysioMimix LC12. Changes in LDH, CYP3A4, and IL-6 after 48 h trovafloxacin exposure with and without LPS in the PhysioMimix LC12 seeded with PHHs (donor HU8373) and non-parenchymal cells (THP-1 cells or Kupffer cells). ( A ) LDH leakage, ( B ) CYP3A4 activity, and ( C ) IL-6 release. Endpoints were normalized to the mean of the pretreatment samples (day 6 of the experiment). Data are plotted as box (interquartile range) and whiskers (min-max) with all individual values shown (n = 2–12). The red dotted line shows 100% (mean of the pretreatment samples). Brackets indicate statistical significance between groups at p < 0.05 by two-way ANOVA with Tukey’s multiple comparisons test.
    Figure Legend Snippet: Immune-mediated toxicity in the PhysioMimix LC12. Changes in LDH, CYP3A4, and IL-6 after 48 h trovafloxacin exposure with and without LPS in the PhysioMimix LC12 seeded with PHHs (donor HU8373) and non-parenchymal cells (THP-1 cells or Kupffer cells). ( A ) LDH leakage, ( B ) CYP3A4 activity, and ( C ) IL-6 release. Endpoints were normalized to the mean of the pretreatment samples (day 6 of the experiment). Data are plotted as box (interquartile range) and whiskers (min-max) with all individual values shown (n = 2–12). The red dotted line shows 100% (mean of the pretreatment samples). Brackets indicate statistical significance between groups at p < 0.05 by two-way ANOVA with Tukey’s multiple comparisons test.

    Techniques Used: Activity Assay

    Related Articles

    Activity Assay:

    Article Title: Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations
    Article Snippet: 2.0 Medium Supplement, 100 nM dexamethasone, and 25 μg/mL gentamicin, and was used for cell culture from day 1 until the end of each experiment. .. Primary human Kupffer cells (NPC-AD-KC, Lot #2118082) and primary human stellate cells (HSC, NPC-AD-SC-P0, Lot #2118082p0) were obtained from LifeNet Health (Virginia Beach, VA). .. Primary human liver sinusoidal endothelial cells (LSEC, ACBRI 566, Lot #566.01.01.01.1T) were obtained from Cell Systems (Kirkland, WA, USA).



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    primary human kupffer cells npc-ad-kc  (LifeNet Health Inc)
    90
    LifeNet Health Inc primary human kupffer cells npc-ad-kc
    Immune-mediated toxicity in the PhysioMimix LC12. Changes in LDH, CYP3A4, and IL-6 after 48 h trovafloxacin exposure with and without LPS in the PhysioMimix LC12 seeded with PHHs (donor HU8373) and non-parenchymal cells (THP-1 cells or <t>Kupffer</t> <t>cells).</t> ( A ) LDH leakage, ( B ) CYP3A4 activity, and ( C ) IL-6 release. Endpoints were normalized to the mean of the pretreatment samples (day 6 of the experiment). Data are plotted as box (interquartile range) and whiskers (min-max) with all individual values shown (n = 2–12). The red dotted line shows 100% (mean of the pretreatment samples). Brackets indicate statistical significance between groups at p < 0.05 by two-way ANOVA with Tukey’s multiple comparisons test.
    Primary Human Kupffer Cells Npc Ad Kc, supplied by LifeNet Health Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/primary+human+kupffer+cells+npc-ad-kc/primary+human+kupffer+cells+npc+ad+kc/pmc10603899-104-0-19
    Average 90 stars, based on 1 article reviews
    primary human kupffer cells npc-ad-kc - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

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    Immune-mediated toxicity in the PhysioMimix LC12. Changes in LDH, CYP3A4, and IL-6 after 48 h trovafloxacin exposure with and without LPS in the PhysioMimix LC12 seeded with PHHs (donor HU8373) and non-parenchymal cells (THP-1 cells or Kupffer cells). ( A ) LDH leakage, ( B ) CYP3A4 activity, and ( C ) IL-6 release. Endpoints were normalized to the mean of the pretreatment samples (day 6 of the experiment). Data are plotted as box (interquartile range) and whiskers (min-max) with all individual values shown (n = 2–12). The red dotted line shows 100% (mean of the pretreatment samples). Brackets indicate statistical significance between groups at p < 0.05 by two-way ANOVA with Tukey’s multiple comparisons test.

    Journal: Bioengineering

    Article Title: Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations

    doi: 10.3390/bioengineering10101195

    Figure Lengend Snippet: Immune-mediated toxicity in the PhysioMimix LC12. Changes in LDH, CYP3A4, and IL-6 after 48 h trovafloxacin exposure with and without LPS in the PhysioMimix LC12 seeded with PHHs (donor HU8373) and non-parenchymal cells (THP-1 cells or Kupffer cells). ( A ) LDH leakage, ( B ) CYP3A4 activity, and ( C ) IL-6 release. Endpoints were normalized to the mean of the pretreatment samples (day 6 of the experiment). Data are plotted as box (interquartile range) and whiskers (min-max) with all individual values shown (n = 2–12). The red dotted line shows 100% (mean of the pretreatment samples). Brackets indicate statistical significance between groups at p < 0.05 by two-way ANOVA with Tukey’s multiple comparisons test.

    Article Snippet: Primary human Kupffer cells (NPC-AD-KC, Lot #2118082) and primary human stellate cells (HSC, NPC-AD-SC-P0, Lot #2118082p0) were obtained from LifeNet Health (Virginia Beach, VA).

    Techniques: Activity Assay